Fluorescence-signaling aptasensor for ATP and PDGF detection on functionalized diamond surface

A. Rahim Ruslinda*, Y. Ishiyama, X. Wang, T. Kobayashi, H. Kawarada


研究成果: Article査読

10 被引用数 (Scopus)


An aminated diamond-based aptasensor is presented for adenosine triphosphate (ATP) and platelet-derived growth factor (PDGF) detection. In this work, a signal-off detection method was employed to provide a sensitive, selective and reusable platform for the simple detection of PDGF and ATP. The detection limit of 0.2 μnM and 0.2 M of PDGF and ATP were achieved, respectively. It was also demonstrated in this study that the aptasensor is selective for PDGF and ATP over other biomolecules. In addition, the reusability of the aptasensor was confirmed by performing multiple cycles, which shows that diamond is a promising candidate as a material for biosensor applications. Moreover, this detection system does not require a target label and it is unaffected by non-specific binding.

ジャーナルJournal of the Electrochemical Society
出版ステータスPublished - 2012

ASJC Scopus subject areas

  • 電子材料、光学材料、および磁性材料
  • 再生可能エネルギー、持続可能性、環境
  • 表面、皮膜および薄膜
  • 電気化学
  • 材料化学


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