Formation of cytochrome C-apatite composite layer on NaOH- and heat-treated titanium

Yu Sogo*, Atsuo Ito, Masahiro Onoguchi, Xia Li, Ayako Oyane, Noboru Ichinose


研究成果: Article査読

4 被引用数 (Scopus)


A cytochrome C (cyt C) and apatite composite layer was formed on a NaOH- and heat-treated titanium substrate (Ti substrate) by immersing the Ti substrate for one day at 25 °C in supersaturated calcium phosphate solutions obtained by mixing infusion fluids. When the initial supersaturation level of the calcium phosphate solution was increased, the total amount of cyt C and apatite deposited on the Ti substrate increased. On the other hand, the cyt C content in the composite layer decreased with an increase in initial supersaturation level. The morphology of the composite layer markedly changed depending on the initial supersaturation level. Therefore, the initial supersaturation level affected the formation of the cyt C and apatite composite layer. It is expected that fibroblast growth factor-2 can be immobilized on NaOH- and heat-treated titanium substrates using the same method.

ジャーナルMaterials Science and Engineering C
出版ステータスPublished - 2009 4月 30

ASJC Scopus subject areas

  • 材料科学(全般)
  • 凝縮系物理学
  • 材料力学
  • 機械工学


「Formation of cytochrome C-apatite composite layer on NaOH- and heat-treated titanium」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。