TY - JOUR
T1 - Formation of cytochrome C-apatite composite layer on NaOH- and heat-treated titanium
AU - Sogo, Yu
AU - Ito, Atsuo
AU - Onoguchi, Masahiro
AU - Li, Xia
AU - Oyane, Ayako
AU - Ichinose, Noboru
PY - 2009/4/30
Y1 - 2009/4/30
N2 - A cytochrome C (cyt C) and apatite composite layer was formed on a NaOH- and heat-treated titanium substrate (Ti substrate) by immersing the Ti substrate for one day at 25 °C in supersaturated calcium phosphate solutions obtained by mixing infusion fluids. When the initial supersaturation level of the calcium phosphate solution was increased, the total amount of cyt C and apatite deposited on the Ti substrate increased. On the other hand, the cyt C content in the composite layer decreased with an increase in initial supersaturation level. The morphology of the composite layer markedly changed depending on the initial supersaturation level. Therefore, the initial supersaturation level affected the formation of the cyt C and apatite composite layer. It is expected that fibroblast growth factor-2 can be immobilized on NaOH- and heat-treated titanium substrates using the same method.
AB - A cytochrome C (cyt C) and apatite composite layer was formed on a NaOH- and heat-treated titanium substrate (Ti substrate) by immersing the Ti substrate for one day at 25 °C in supersaturated calcium phosphate solutions obtained by mixing infusion fluids. When the initial supersaturation level of the calcium phosphate solution was increased, the total amount of cyt C and apatite deposited on the Ti substrate increased. On the other hand, the cyt C content in the composite layer decreased with an increase in initial supersaturation level. The morphology of the composite layer markedly changed depending on the initial supersaturation level. Therefore, the initial supersaturation level affected the formation of the cyt C and apatite composite layer. It is expected that fibroblast growth factor-2 can be immobilized on NaOH- and heat-treated titanium substrates using the same method.
KW - Composite layer
KW - Cytochrome C
KW - NaOH- and heat-treated titanium
KW - Supersaturated calcium phosphate solution
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U2 - 10.1016/j.msec.2008.07.008
DO - 10.1016/j.msec.2008.07.008
M3 - Article
AN - SCOPUS:64749115071
SN - 0928-4931
VL - 29
SP - 766
EP - 770
JO - Materials Science and Engineering C
JF - Materials Science and Engineering C
IS - 3
ER -