@article{18e8363aefbc4f10995c41acd7d95937,
title = "Gold-Catalyzed Cascade and Divergent Synthesis of Indolobenzazepines and Indoloquinolines from Nitrogen-Tethered 1,8-Diynes",
abstract = "We describe the divergent construction of two nitrogen-containing polycyclic systems by gold-catalyzed cycloisomerizations. The gold-catalyzed cascade hydroamination and 7-endo-dig-selective cycloisomerization of nitrogen-tethered 1,8-diynes yielded indolo[1,7-ab]benzazepines in one pot. In contrast, when Johnphos-coordinated gold catalyst was used, the same 1,8-diynes were transformed into indolo[1,2-a]quinolines by 6-endo-dig-selective cycloisomerization along with rearrangement of the substituent on one of the alkynes. The reaction of a naphthalene-tethered substrate provided a helically chiral aza[6]helicene.",
keywords = "Alkynes, Cycloisomerization, Divergent synthesis, Gold, Silver",
author = "Mamoru Ito and Hideaki Onoda and Asahi Takaki and Takanori Shibata",
note = "Funding Information: This wok was supported by Waseda University Grant for Special Research Projects (2021C‐186). Dr. M. Ito thanks Tokyo Ohka Foundation for the Promotion of Science and Technology for its support. Funding Information: This wok was supported by Waseda University Grant for Special Research Projects (2021C-186). Dr. M. Ito thanks Tokyo Ohka Foundation for the Promotion of Science and Technology for its support. Publisher Copyright: {\textcopyright} 2021 Wiley-VCH GmbH.",
year = "2022",
month = apr,
day = "21",
doi = "10.1002/ejoc.202101337",
language = "English",
volume = "2022",
journal = "European Journal of Organic Chemistry",
issn = "1434-193X",
publisher = "Wiley-VCH Verlag",
number = "15",
}