TY - GEN
T1 - Hemocompatibility of DLC coating for blood analysis devices
AU - Shiba, K.
AU - Ohgoe, Y.
AU - Hirakuri, K.
AU - Mizuno, J.
AU - Shoji, S.
AU - Ozeki, K.
AU - Sato, K.
AU - Fukata, N.
AU - Alanazi, A.
PY - 2014/1/1
Y1 - 2014/1/1
N2 - The studies of Diamond-Like carbon (DLC) coated medical devices have reported possibility for developing blood analysis devices. DLC film is a surface modification technique for biomaterials due to their hemocompatibility, low friction, and reasonableness. We have deposited DLC film on silicon (Si), cyclic olefin polymer (COP), polycarbonate (PC), SU-8 and polydimethylsiloxane (PDMS) by using r.f. plasma enhanced chemical vapor deposition (r.f.-PECVD) method. These materials have been used extensively in micro-channel devices. The hemocompatibility, chemical composition, structure, wettability, roughness, and surface morphology of the samples have been investigated by in-vitro test with sheep blood, X-ray photoelectron spectroscopy (XPS), Raman spectroscopy (Raman), a contact angle measurement, atomic force microscopy (AFM). The result indicated that the satisfied hemocompatibility was obtained for the DLC on COP and PDMS. Moreover, it was observed that hemocompatibility was influenced by surface conditions of sample DLC coating to COP and PDMS are expected as a surface modification technique for the micro-channel with hemocompatibility.
AB - The studies of Diamond-Like carbon (DLC) coated medical devices have reported possibility for developing blood analysis devices. DLC film is a surface modification technique for biomaterials due to their hemocompatibility, low friction, and reasonableness. We have deposited DLC film on silicon (Si), cyclic olefin polymer (COP), polycarbonate (PC), SU-8 and polydimethylsiloxane (PDMS) by using r.f. plasma enhanced chemical vapor deposition (r.f.-PECVD) method. These materials have been used extensively in micro-channel devices. The hemocompatibility, chemical composition, structure, wettability, roughness, and surface morphology of the samples have been investigated by in-vitro test with sheep blood, X-ray photoelectron spectroscopy (XPS), Raman spectroscopy (Raman), a contact angle measurement, atomic force microscopy (AFM). The result indicated that the satisfied hemocompatibility was obtained for the DLC on COP and PDMS. Moreover, it was observed that hemocompatibility was influenced by surface conditions of sample DLC coating to COP and PDMS are expected as a surface modification technique for the micro-channel with hemocompatibility.
KW - blood analysis
KW - diamond-like carbon (DLC)
KW - hemocompatibility
KW - micro channel
KW - micro fluidic device
UR - http://www.scopus.com/inward/record.url?scp=84903746699&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84903746699&partnerID=8YFLogxK
U2 - 10.1109/ICEP.2014.6826781
DO - 10.1109/ICEP.2014.6826781
M3 - Conference contribution
AN - SCOPUS:84903746699
SN - 9784904090107
T3 - 2014 International Conference on Electronics Packaging, ICEP 2014
SP - 748
EP - 751
BT - 2014 International Conference on Electronics Packaging, ICEP 2014
PB - IEEE Computer Society
T2 - 2014 International Conference on Electronics Packaging, ICEP 2014
Y2 - 23 April 2014 through 25 April 2014
ER -