抄録
Potentiometric creatinine microsensors were fabricated by use of a composite film consisting of polyion complex (PIC) which contains creatinine iminohydrolase (CIH), and the electrochemically inactive polypyrrole (iPPy). The PPy/PIC-CIH composite film electrode displayed potential response to creatinine concentration owing to a pH change occurring during the enzymatic reaction. The sensitivity was varied by using different polyions of the PIC. With poly-L-lysine and sebacic acid, the iPPy/PIC-CIH electrode demonstrated a high sensitivity (29.8 mV decade-1) and a low detection limit (1 × 10-6 mol dm-3), which allow one to monitor creatinine concentration in the physiological range.
本文言語 | English |
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ページ(範囲) | 406-408 |
ページ数 | 3 |
ジャーナル | Journal of the Electrochemical Society |
巻 | 145 |
号 | 2 |
DOI | |
出版ステータス | Published - 1998 2月 |
ASJC Scopus subject areas
- 電子材料、光学材料、および磁性材料
- 再生可能エネルギー、持続可能性、環境
- 表面、皮膜および薄膜
- 電気化学
- 材料化学