TY - GEN
T1 - How to ensure safety factors in the development of artificial heart
T2 - 2007 International Conference on Life System Modeling and Simulation, LSMS 2007
AU - Umezu, Mitsuo
PY - 2007/12/1
Y1 - 2007/12/1
N2 - The author has involved in two types of clinically available artificial hearts in Japan for these 30 years. Firstly, Toyobo auxiliary pulsatile ventricular assist pump was commercialized in 1991 and over 700 clinical cases are reported in Japanese market. Secondly, an implantable non-pulsatile ventricular assist pump (EVAHEART, Sunmedical Tech. Res. Co.) has been implanted into 11 patients in Japan. The author has been establishing a methodology to eliminate considerable risk factors through a development of hydrodynamic performance test, durability test and biocompatibility test. These in vitro tests are all effective to ensure a safety of the system and also in vitro tests have a contribution to reduce a number of animal experiments.
AB - The author has involved in two types of clinically available artificial hearts in Japan for these 30 years. Firstly, Toyobo auxiliary pulsatile ventricular assist pump was commercialized in 1991 and over 700 clinical cases are reported in Japanese market. Secondly, an implantable non-pulsatile ventricular assist pump (EVAHEART, Sunmedical Tech. Res. Co.) has been implanted into 11 patients in Japan. The author has been establishing a methodology to eliminate considerable risk factors through a development of hydrodynamic performance test, durability test and biocompatibility test. These in vitro tests are all effective to ensure a safety of the system and also in vitro tests have a contribution to reduce a number of animal experiments.
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M3 - Conference contribution
AN - SCOPUS:38049129742
SN - 9783540747703
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 88
EP - 96
BT - Life System Modeling and Simulation - International Conference, LSMS 2007, Proceedings
Y2 - 14 September 2007 through 17 September 2007
ER -