@article{a6c430a34aa84df2ba3d2af65761c04a,
title = "Identification of region-specific transcription factor genes in the adult mouse brain by medium-scale real-time RT-PCR",
abstract = "We established a medium-scale real-time RT-PCR system focusing on transcription factors and applied it to their expression profiles in the adult mouse 11 brain regions (http://genome.gsc.riken.jp/qRT-PCR/). Almost 90% of the examined genes showed significant expression in at least one region. We successfully extracted 179 region-specific genes by clustering analysis. Interestingly, the transcription factors involved in the development of the pituitary were still expressed in the adult pituitary, suggesting that they also play important roles in maintenance of the pituitary. These results provide unique molecular markers that may account for the molecular basis of the unique functions of specific brain regions.",
keywords = "Real-time RT-PCR, Region-specific, Transcription factor",
author = "Harukazu Suzuki and Rie Okunishi and Wataru Hashizume and Shintaro Katayama and Noriko Ninomiya and Naoki Osato and Kenjiro Sato and Mari Nakamura and Juri Iida and Mutsumi Kanamori and Yoshihide Hayashizaki",
note = "Funding Information: We thank Dr. K. Polland (UCSC) for providing the HOPACH program and A. Hasegawa for technical assistance. We also thank the members of the Laboratory for Genome Exploration Research Group. This study was supported by MEXT Research Grants for the RIKEN Genome Exploration Research Project, for Advanced and Innovational Research Program in Life Science and for National Project on Genome Network Analysis to Y.H.",
year = "2004",
month = aug,
day = "27",
doi = "10.1016/j.febslet.2004.07.068",
language = "English",
volume = "573",
pages = "214--218",
journal = "FEBS Letters",
issn = "0014-5793",
publisher = "Elsevier",
number = "1-3",
}