@inproceedings{9ddcbb8d29124057aec798bf8d951460,
title = "In vitro selection of novel peptide agonists for human somatostatin receptor subtype-2 using a water-in-oil microdroplet platform",
abstract = "Here we present an in vitro selection method to obtain peptide agonists for G protein-coupled receptors (GPCRs) using a water-in-oil (W/O) microdroplet platform. Using this method, we successfully identified novel peptide agonists for human somatostatin receptor subtype-2 (SSTR2) from a library of partially randomized SST sequences. This result demonstrates that our method will be a powerful platform for identifying novel peptide agonists for human GPCRs with known and unknown endogenous ligands.",
keywords = "G protein-coupled receptor, Microdroplet, Peptide agonist, Yeast",
author = "T. Sakurai and R. Iizuka and Y. Nakamura and J. Ishii and A. Kondo and A. Iguchi and Yoon, {D. H.} and T. Sekiguchi and S. Shoji and T. Funatsu",
year = "2016",
language = "English",
series = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
publisher = "Chemical and Biological Microsystems Society",
pages = "593--594",
booktitle = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",
note = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 ; Conference date: 09-10-2016 Through 13-10-2016",
}