Intracellular click reaction with a fluorescent chemical Ca2+ indicator to prolong its cytosolic retention

Yoshiaki Takei; Atsushi Murata; Kento Yamagishi; Satoshi Arai; Hideki Nakamura; Takafumi Inoue; Shinji Takeoka

doi:10.1039/c3cc42489h

Intracellular click reaction with a fluorescent chemical Ca²⁺ indicator to prolong its cytosolic retention

Yoshiaki Takei, Atsushi Murata, Kento Yamagishi, Satoshi Arai, Hideki Nakamura, Takafumi Inoue, Shinji Takeoka^*

^*この研究の対応する著者

先進理工学部

研究成果: Article › 査読

8 被引用数 (Scopus)

抄録

The powerful strategy of “intracellular click reaction” was used to retain a chemical Ca²⁺ indicator in the cytosol. Specifically, a novel clickable Ca²⁺ indicator “N₃-fura-2 AM” was coupled with dibenzylcyclooctyl-modified biomacromolecules via copper-free click reaction in living cells and Ca²⁺ oscillation was observed for an extended period of time.

本文言語	English
ページ（範囲）	7313-7315
ページ数	3
ジャーナル	Chemical Communications
巻	49
号	66
DOI	https://doi.org/10.1039/c3cc42489h
出版ステータス	Published - 2013 7月 23

ASJC Scopus subject areas

触媒
電子材料、光学材料、および磁性材料
セラミックおよび複合材料
化学一般
表面、皮膜および薄膜
金属および合金
材料化学

文献へのアクセス

10.1039/c3cc42489h

他のファイルとリンク

引用スタイル

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AU - Inoue, Takafumi

AU - Takeoka, Shinji

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