Intraoperative local demarcation system of brain tumor based on 5-aminolaevulinic acid induced porphyrin fluorescence

Takehiro Ando*, M. Noguch, K. Shimaya, K. Wang, E. Kobayashi, H. Liao, T. Maruyama, Y. Mulagaki, H. Iseki, I. Sakuma

*この研究の対応する著者

    研究成果: Conference contribution

    抄録

    A lightweight intraoperative spectrum measurement system for 5-ALA induced PpIX fluorescence was developed. The developed system includes a semiconductor LASER for excitation light (output light wavelength: 405nm), a CCD spectrometer, optical fiber coupled on lens system and PC. The first prototype device has a bundled fiber which contains 6 excitation fibers around one measurement fiber. The second one uses a dichroic mirror which reflects blue light (λ≤550nm) and transmits other wavelength. The third one contains not only a dichroic mirror but also a long path filter (cut on: λ=570nm) and has improved mechanical strength. The weight of the first and the prototype probe is 45g, and the external diameter is 11mm.. The weight of this probe is 25g and the external diameter is 18mm. The probes can be positioned manually and measure 5-ALA induced PpIX fluorescence.

    本文言語English
    ホスト出版物のタイトル7th Asian-Pacific Conference on Medical and Biological Engineering, APCMBE 2008
    出版社Springer Verlag
    ページ754-757
    ページ数4
    ISBN(印刷版)9783540790389
    DOI
    出版ステータスPublished - 2008

    出版物シリーズ

    名前IFMBE Proceedings
    19 IFMBE
    ISSN(印刷版)1680-0737

    ASJC Scopus subject areas

    • バイオエンジニアリング
    • 生体医工学

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