TY - JOUR
T1 - Ir-catalyzed synthesis of substituted tribenzosilepins by dehydrogenative C-H/Si-H coupling
AU - Shibata, Takanori
AU - Uno, Ninna
AU - Sasaki, Tomoya
AU - Takano, Hideaki
AU - Sato, Tatsuki
AU - Kanyiva, Stephen Kyalo
PY - 2018/4/6
Y1 - 2018/4/6
N2 - The Ir-catalyzed intramolecular reaction of 2′,6′-diaryl-2-(hydrosilyl)biphenyls gave substituted tribenzosilepins by direct dehydrogenative C-H/Si-H coupling. This is the first example of catalytic construction of the tribenzosilepin skeleton. Enantiomerically pure tribenzosilepin was prepared by optical resolution using chiral HPLC, and its inversion barrier was calculated by measurement of rate of racemization using the Eyring kinetic equation under heating conditions.
AB - The Ir-catalyzed intramolecular reaction of 2′,6′-diaryl-2-(hydrosilyl)biphenyls gave substituted tribenzosilepins by direct dehydrogenative C-H/Si-H coupling. This is the first example of catalytic construction of the tribenzosilepin skeleton. Enantiomerically pure tribenzosilepin was prepared by optical resolution using chiral HPLC, and its inversion barrier was calculated by measurement of rate of racemization using the Eyring kinetic equation under heating conditions.
UR - http://www.scopus.com/inward/record.url?scp=85045126865&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85045126865&partnerID=8YFLogxK
U2 - 10.1021/acs.joc.8b00233
DO - 10.1021/acs.joc.8b00233
M3 - Article
C2 - 29554427
AN - SCOPUS:85045126865
SN - 0022-3263
VL - 83
SP - 3426
EP - 3432
JO - Journal of Organic Chemistry
JF - Journal of Organic Chemistry
IS - 7
ER -