TY - JOUR
T1 - Lipidheme vesicles and hemoglobin vesicles as dioxygen infusion
AU - Komatsu, Teruyuki
AU - Takeoka, Shinji
AU - Sakai, Hiromi
AU - Tsuchida, Eishun
PY - 1999/3/1
Y1 - 1999/3/1
N2 - The structure, physicochemical properties, O2-binding ability of lipidheme vesicles and hemoglobin (Hb) vesicles were evaluated. The solution properties of lipidheme vesicles and Hb-vesicles are low in comparison to blood, due to their small sizes. The O2-binding rate of Hb is affected by encapsulation. In fact, the O2-association of Hb vesicles is slower than that of Hb itself, but faster than that of the red blood cell. Since the lipidheme locates in the bilayer membrane, lipidheme shows a faster O2-binding rate constant than Hb. Inspite of structural differences, both materials can act as dioxygen infusion.
AB - The structure, physicochemical properties, O2-binding ability of lipidheme vesicles and hemoglobin (Hb) vesicles were evaluated. The solution properties of lipidheme vesicles and Hb-vesicles are low in comparison to blood, due to their small sizes. The O2-binding rate of Hb is affected by encapsulation. In fact, the O2-association of Hb vesicles is slower than that of Hb itself, but faster than that of the red blood cell. Since the lipidheme locates in the bilayer membrane, lipidheme shows a faster O2-binding rate constant than Hb. Inspite of structural differences, both materials can act as dioxygen infusion.
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M3 - Conference article
AN - SCOPUS:0033092633
SN - 0032-3934
VL - 40
JO - American Chemical Society, Polymer Preprints, Division of Polymer Chemistry
JF - American Chemical Society, Polymer Preprints, Division of Polymer Chemistry
IS - 1
T2 - Proceedings of the 1999 ACS Anaheim Meeting
Y2 - 21 March 1999 through 25 March 1999
ER -