TY - JOUR
T1 - Luminescence imaging of water during uniform-field irradiation by spot scanning proton beams
AU - Komori, Masataka
AU - Sekihara, Eri
AU - Yabe, Takuya
AU - Horita, Ryo
AU - Toshito, Toshiyuki
AU - Yamamoto, Seiichi
N1 - Funding Information:
The measurements in this study were performed at Nagoya Proton Therapy Center. We thank the clinical teams for allowing us beam times for our experiments as well as the medical physicists who helped us prepare and carry out the irradiations. This work was supported in part by JSPS KAKENHI Grant Number JP25253077, JP16H03908 and JP16K15349.
Publisher Copyright:
© 2018 Institute of Physics and Engineering in Medicine.
PY - 2018/5/29
Y1 - 2018/5/29
N2 - Luminescence was found during pencil-beam proton irradiation to water phantom and range could be estimated from the luminescence images. However, it is not yet clear whether the luminescence imaging is applied to the uniform fields made of spot-scanning proton-beam irradiations. For this purpose, imaging was conducted for the uniform fields having spread out Bragg peak (SOBP) made by spot scanning proton beams. We designed six types of the uniform fields with different ranges, SOBP widths and irradiation fields. One of the designed fields was irradiated to water phantom and a cooled charge coupled device camera was used to measure the luminescence image during irradiations. We estimated the ranges, field widths, and luminescence intensities from the luminescence images and compared those with the dose distribution calculated by a treatment planning system. For all types of uniform fields, we could obtain clear images of the luminescence showing the SOBPs. The ranges and field widths evaluated from the luminescence were consistent with those of the dose distribution calculated by a treatment planning system within the differences of -4 mm and -11 mm, respectively. Luminescence intensities were almost proportional to the SOBP widths perpendicular to the beam direction. The luminescence imaging could be applied to uniform fields made of spot scanning proton beam irradiations. Ranges and widths of the uniform fields with SOBP could be estimated from the images. The luminescence imaging is promising for the range and field width estimations in proton therapy.
AB - Luminescence was found during pencil-beam proton irradiation to water phantom and range could be estimated from the luminescence images. However, it is not yet clear whether the luminescence imaging is applied to the uniform fields made of spot-scanning proton-beam irradiations. For this purpose, imaging was conducted for the uniform fields having spread out Bragg peak (SOBP) made by spot scanning proton beams. We designed six types of the uniform fields with different ranges, SOBP widths and irradiation fields. One of the designed fields was irradiated to water phantom and a cooled charge coupled device camera was used to measure the luminescence image during irradiations. We estimated the ranges, field widths, and luminescence intensities from the luminescence images and compared those with the dose distribution calculated by a treatment planning system. For all types of uniform fields, we could obtain clear images of the luminescence showing the SOBPs. The ranges and field widths evaluated from the luminescence were consistent with those of the dose distribution calculated by a treatment planning system within the differences of -4 mm and -11 mm, respectively. Luminescence intensities were almost proportional to the SOBP widths perpendicular to the beam direction. The luminescence imaging could be applied to uniform fields made of spot scanning proton beam irradiations. Ranges and widths of the uniform fields with SOBP could be estimated from the images. The luminescence imaging is promising for the range and field width estimations in proton therapy.
KW - field size estimation
KW - luminescence imaging
KW - proton beam
KW - uniform field
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U2 - 10.1088/1361-6560/aac223
DO - 10.1088/1361-6560/aac223
M3 - Article
C2 - 29722295
AN - SCOPUS:85048231025
SN - 0031-9155
VL - 63
JO - Physics in Medicine and Biology
JF - Physics in Medicine and Biology
IS - 11
M1 - 11NT01
ER -