Metastability of supersaturated solution and nucleation

Noriaki Kubota*, Masanori Kobari, Izumi Hirasawa


研究成果: Chapter


A certain time may elapse for the occurrence of a first nucleation after a solution is made supersaturated. Thus, the supersaturated solution looks as if it could be in a metastable state though in a limited time. Such metastability of a supersaturated solution has been evaluated (rather technically) by the magnitude of the metastable zone width (MSZW), i.e., the supercooling at which a first nucleation event is detected when supersaturation is increased by cooling, or the induction time, i.e., the time elapsed until a first nucleation event is detected at a constant temperature. The larger these values are, the higher themetastability is. Surprisingly, however, these two nucleation-related quantities are not clearly understood. There is still much confusion. This chapter provides an overview of recent understandings of the MSZW and induction time with focus on the problems of (1) stochastic and deterministic aspects, (2) time-dependent change of solution structure, (3) role of nucleation, and (4) relevance to the operation of an industrial batch crystallizer.

ホスト出版物のタイトルAdvances in Organic Crystal Chemistry
ホスト出版物のサブタイトルComprehensive Reviews 2015
出版社Springer Japan
出版ステータスPublished - 2015 8月 6

ASJC Scopus subject areas

  • 化学 (全般)
  • 工学(全般)
  • 物理学および天文学(全般)


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