抄録
A neuraminidase inhibitor, nobiloside (1), was isolated from the marine sponge Erylus nobilis Thiele, 1903. Its structure was determined as a penasterol trisaccharide. The absolute configurations were determined by NMR and chiral GC analysis. It inhibited neuraminidase from the bacterium Clostridium perfringens with an IC50 value of 0.46μg/mL.
本文言語 | English |
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ページ(範囲) | 411-413 |
ページ数 | 3 |
ジャーナル | Journal of Natural Products |
巻 | 65 |
号 | 3 |
DOI | |
出版ステータス | Published - 2002 4月 9 |
外部発表 | はい |
ASJC Scopus subject areas
- 分析化学
- 分子医療
- 薬理学
- 薬科学
- 創薬
- 補完代替医療
- 有機化学