TY - JOUR
T1 - Palladium-Catalyzed Decarbonylative Cross-Coupling of Azinecarboxylates with Arylboronic Acids
AU - Muto, Kei
AU - Hatakeyama, Taito
AU - Itami, Kenichiro
AU - Yamaguchi, Junichiro
N1 - Funding Information:
This work was supported by the ERATO program from JST (K.I.) and JSPS KAKENHI (Grant Nos. JP16H01011 and JP16H04148 (to J.Y.). K.M. was supported by the Early Bird Program of Waseda University. We thank Mr. Ryosuke Takise (Nagoya University) for providing starting materials. ITbM is supported by the World Premier International Research Center (WPI) Initiative, Japan.
Publisher Copyright:
© 2016 American Chemical Society.
PY - 2016/10/7
Y1 - 2016/10/7
N2 - The first palladium-catalyzed decarbonylative coupling of phenyl 2-azinecarboxylates and arylboronic acids is presented. The key for the development of this decarbonylative coupling is the use of Pd/dcype as a catalyst. A wide range of 2-azinecarboxylates can undergo the present coupling reaction to afford 2-arylazines. By combination with previously reported nickel-catalyzed decarbonylative coupling, we achieved a chemoselective sequential decarbonylative coupling of pyridine dicarboxylate to synthesize 2,4-diarylpyridine.
AB - The first palladium-catalyzed decarbonylative coupling of phenyl 2-azinecarboxylates and arylboronic acids is presented. The key for the development of this decarbonylative coupling is the use of Pd/dcype as a catalyst. A wide range of 2-azinecarboxylates can undergo the present coupling reaction to afford 2-arylazines. By combination with previously reported nickel-catalyzed decarbonylative coupling, we achieved a chemoselective sequential decarbonylative coupling of pyridine dicarboxylate to synthesize 2,4-diarylpyridine.
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U2 - 10.1021/acs.orglett.6b02556
DO - 10.1021/acs.orglett.6b02556
M3 - Article
AN - SCOPUS:84990855057
SN - 1523-7060
VL - 18
SP - 5106
EP - 5109
JO - Organic Letters
JF - Organic Letters
IS - 19
ER -