TY - JOUR
T1 - Potential response of monolayer-modified indium tin oxide electrodes to indole compounds
AU - Nakanishi, Takuya
AU - Ueno, Tsubasa
AU - Matsunaga, Mariko
AU - Khan, Md Zaved Hossain
AU - Osaka, Tetsuya
PY - 2010/2
Y1 - 2010/2
N2 - Potential response of indium tin oxide (ITO) electrode modified by treatment with disuccinimidyl suberate (DSS) was investigated to various target molecules. Distinctively, the DSS-modified ITO electrode exhibited a potential shift to the molecules possessing an indole group such as tryptophan, tryptamine and indole propionic acid, while little response to benzoic acid, phenylalanine, proline, proline amide, and arginine was observed. In addition, the combination of this specificity to indoles and enantioselective affinity of human serum albumin (HSA), which was additionally immobilized on the DSS-modified ITO electrode, brought about enantioselective potential response to tryptophan.
AB - Potential response of indium tin oxide (ITO) electrode modified by treatment with disuccinimidyl suberate (DSS) was investigated to various target molecules. Distinctively, the DSS-modified ITO electrode exhibited a potential shift to the molecules possessing an indole group such as tryptophan, tryptamine and indole propionic acid, while little response to benzoic acid, phenylalanine, proline, proline amide, and arginine was observed. In addition, the combination of this specificity to indoles and enantioselective affinity of human serum albumin (HSA), which was additionally immobilized on the DSS-modified ITO electrode, brought about enantioselective potential response to tryptophan.
KW - Chiral sensors
KW - Indium tin oxide
KW - Indole compounds
KW - Monolayer modification
KW - Potentiometric detection
KW - Sensors
UR - http://www.scopus.com/inward/record.url?scp=76549090162&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=76549090162&partnerID=8YFLogxK
U2 - 10.1002/elan.200900420
DO - 10.1002/elan.200900420
M3 - Article
AN - SCOPUS:76549090162
SN - 1040-0397
VL - 22
SP - 393
EP - 398
JO - Electroanalysis
JF - Electroanalysis
IS - 4
ER -