Practical approach for hydroheteroarylation of alkynes using bench-stable catalyst

Kyalo Stephen Kanyiva; Yoshiaki Nakao; Tamejiro Hiyama

doi:10.3987/com-06-s(k)29

Practical approach for hydroheteroarylation of alkynes using bench-stable catalyst

Kyalo Stephen Kanyiva^*, Yoshiaki Nakao, Tamejiro Hiyama

^*この研究の対応する著者

研究成果: Article › 査読

36 被引用数 (Scopus)

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A simple and convenient method for hydroheteroarylation of alkynes using air- stable catalyst precursors is described. The addition of a solution of AlMe₃ in hexane to Ni(acac)₂ and tri(cyclopentyl)phosphonium tetrafluoroborate ([Cyp₃PH\BF₄) rapidly generates an active Ni(0)/Cyp₃P catalyst for cis-hydroheteroarylation of alkynes under mild conditions. The catalytic reaction is applicable to a wide range of heteroarenes to give heteroaryl-substituted ethenes in excellent stereo- and regioselectivities.

本文言語	English
ページ（範囲）	677-680
ページ数	4
ジャーナル	Heterocycles
巻	72
DOI	https://doi.org/10.3987/com-06-s(k)29
出版ステータス	Published - 2007 4月 13
外部発表	はい

ASJC Scopus subject areas

分析化学
薬理学
有機化学

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10.3987/com-06-s(k)29

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abstract = "A simple and convenient method for hydroheteroarylation of alkynes using air- stable catalyst precursors is described. The addition of a solution of AlMe3 in hexane to Ni(acac)2 and tri(cyclopentyl)phosphonium tetrafluoroborate ([Cyp3PH\BF4) rapidly generates an active Ni(0)/Cyp3P catalyst for cis-hydroheteroarylation of alkynes under mild conditions. The catalytic reaction is applicable to a wide range of heteroarenes to give heteroaryl-substituted ethenes in excellent stereo- and regioselectivities.",

author = "Kanyiva, {Kyalo Stephen} and Yoshiaki Nakao and Tamejiro Hiyama",

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doi = "10.3987/com-06-s(k)29",

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AU - Kanyiva, Kyalo Stephen

AU - Nakao, Yoshiaki

AU - Hiyama, Tamejiro

PY - 2007/4/13

Y1 - 2007/4/13

N2 - A simple and convenient method for hydroheteroarylation of alkynes using air- stable catalyst precursors is described. The addition of a solution of AlMe3 in hexane to Ni(acac)2 and tri(cyclopentyl)phosphonium tetrafluoroborate ([Cyp3PH\BF4) rapidly generates an active Ni(0)/Cyp3P catalyst for cis-hydroheteroarylation of alkynes under mild conditions. The catalytic reaction is applicable to a wide range of heteroarenes to give heteroaryl-substituted ethenes in excellent stereo- and regioselectivities.

AB - A simple and convenient method for hydroheteroarylation of alkynes using air- stable catalyst precursors is described. The addition of a solution of AlMe3 in hexane to Ni(acac)2 and tri(cyclopentyl)phosphonium tetrafluoroborate ([Cyp3PH\BF4) rapidly generates an active Ni(0)/Cyp3P catalyst for cis-hydroheteroarylation of alkynes under mild conditions. The catalytic reaction is applicable to a wide range of heteroarenes to give heteroaryl-substituted ethenes in excellent stereo- and regioselectivities.

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SN - 0385-5414

VL - 72

SP - 677

EP - 680

JO - Heterocycles

JF - Heterocycles

ER -

Practical approach for hydroheteroarylation of alkynes using bench-stable catalyst

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