Preparation of methotrexate-encapsulated liposomes and evaluation of their properties

Kvoko Kaiyama; Izumi Sato; Shinji Takeoka

Preparation of methotrexate-encapsulated liposomes and evaluation of their properties

Kvoko Kaiyama^*, Izumi Sato, Shinji Takeoka

^*この研究の対応する著者

先進理工学部

研究成果: Paper › 査読

抄録

We are preparing immunoliposomes which encapsulate anticancer methotrexate to provide an efficient intracellular drug delivery system (DDS) in tumor cells. In this paper, concentrated methotrexate was encapsulated into liposomes by an extrusion method. We also evaluated properties of the liposomes such as particle size, encapsulation efficiency, dispersibility, and the leakage of MIX from liposomes.

本文言語	English
ページ数	1
出版ステータス	Published - 2006 12月 1
イベント	55th Society of Polymer Science Japan Symposium on Macromolecules - Toyama, Japan 継続期間: 2006 9月 20 → 2006 9月 22

Other

Other	55th Society of Polymer Science Japan Symposium on Macromolecules
国/地域	Japan
City	Toyama
Period	06/9/20 → 06/9/22

ASJC Scopus subject areas

工学（全般）

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引用スタイル

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title = "Preparation of methotrexate-encapsulated liposomes and evaluation of their properties",

abstract = "We are preparing immunoliposomes which encapsulate anticancer methotrexate to provide an efficient intracellular drug delivery system (DDS) in tumor cells. In this paper, concentrated methotrexate was encapsulated into liposomes by an extrusion method. We also evaluated properties of the liposomes such as particle size, encapsulation efficiency, dispersibility, and the leakage of MIX from liposomes.",

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AU - Kaiyama, Kvoko

AU - Sato, Izumi

AU - Takeoka, Shinji

PY - 2006/12/1

Y1 - 2006/12/1

N2 - We are preparing immunoliposomes which encapsulate anticancer methotrexate to provide an efficient intracellular drug delivery system (DDS) in tumor cells. In this paper, concentrated methotrexate was encapsulated into liposomes by an extrusion method. We also evaluated properties of the liposomes such as particle size, encapsulation efficiency, dispersibility, and the leakage of MIX from liposomes.

AB - We are preparing immunoliposomes which encapsulate anticancer methotrexate to provide an efficient intracellular drug delivery system (DDS) in tumor cells. In this paper, concentrated methotrexate was encapsulated into liposomes by an extrusion method. We also evaluated properties of the liposomes such as particle size, encapsulation efficiency, dispersibility, and the leakage of MIX from liposomes.

KW - Anticancer

KW - DDS

KW - Liposomes

KW - Methotrexate

KW - Vesicles

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M3 - Paper

AN - SCOPUS:33846169451

T2 - 55th Society of Polymer Science Japan Symposium on Macromolecules

Y2 - 20 September 2006 through 22 September 2006

ER -

Preparation of methotrexate-encapsulated liposomes and evaluation of their properties

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