抄録
Purpose: To point out the advantages and drawbacks of high-dose rate brachytherapy in the treatment of mobile tongue cancer and indicate the clinical importance of modular lead-lined spacers when applying this technique to patients. Methods: First, all basic steps to construct the modular spacer are shown. Second, we simulate and evaluate the dose rate reduction for a wide range of spacer configurations. Results: With increasing distance to the source absorbed doses dropped considerably. Significantly more shielding was obtained when lead was added to the spacer and this effect was most pronounced on shorter (i.e. more clinically relevant) distances to the source. Conclusions: The modular spacer represents an important addition to the planning and treatment stages of mobile tongue cancer using HDR-ISBT.
本文言語 | English |
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論文番号 | e0154226 |
ジャーナル | PLoS One |
巻 | 11 |
号 | 4 |
DOI | |
出版ステータス | Published - 2016 4月 1 |
外部発表 | はい |
ASJC Scopus subject areas
- 農業および生物科学(全般)
- 生化学、遺伝学、分子生物学(全般)
- 医学(全般)