抄録
An oral administration of χ-tocotrienol (χ-T3) or χ-tocopherol (χ-Toc) to male rats caused an increase of the concentration of 2,7,8-trimethyl-2-(β-carboxyethyl)-6-hydroxy chroman (LLU-α, χ-CEHC), a natriuretic compound, in plasma with a T(m)(a)(x) of 9 h. The configuration at C-2 of LLU-α produced from χ-T3 or χ-Toc was assigned as S-form by an HPLC equipped with a chiral column. These data indicated that LLU-α was produced not only from χ-Toc but also χ-T3, without racemization at C-2 in rats.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 1395-1397 |
| ページ数 | 3 |
| ジャーナル | Biological and Pharmaceutical Bulletin |
| 巻 | 23 |
| 号 | 11 |
| 出版ステータス | Published - 2000 |
| 外部発表 | はい |
ASJC Scopus subject areas
- 分子医療
- 薬理学、毒性学および薬学（全般）