TY - JOUR
T1 - Relationships between lifestyle factors and neutrophil functions in the elderly
AU - Tsukamoto, Kazumasa
AU - Suzuki, Katsuhiko
AU - Machida, Kazuhiko
AU - Saiki, Chinatsu
AU - Murayama, Rumiko
AU - Sugita, Minoru
PY - 2002
Y1 - 2002
N2 - We investigated the relationships between neutrophil functions and lifestyle factors in the elderly. The subjects (84 males, 73.9±5.8 years old; and 63 females, 70.0±4.6 years old) belonged to a recreational seniors club in Japan. Investigations of the subjects' stress, exercise habits, smoking habits, and alcohol-drinking habits were performed. The phagocytosis and superoxide productivity of the neutrophils were measured with a nitroblue tetrazolium (NBT) reduction test. In addition, leukocyte counts and serum total protein (TP) levels were determined. The results revealed that aging, high serum levels, and stress-coping factors (e.g., having hobbies, keeping pets, and close links with friends or family) significantly correlated with preferable neutrophil functions. In addition, significant effects of lifestyle factors on the balance between phagocytosis and subsequent superoxide production were observed. Thus, the results of the present study suggest that there are correlations between neutrophil functions and lifestyle factors in the elderly.
AB - We investigated the relationships between neutrophil functions and lifestyle factors in the elderly. The subjects (84 males, 73.9±5.8 years old; and 63 females, 70.0±4.6 years old) belonged to a recreational seniors club in Japan. Investigations of the subjects' stress, exercise habits, smoking habits, and alcohol-drinking habits were performed. The phagocytosis and superoxide productivity of the neutrophils were measured with a nitroblue tetrazolium (NBT) reduction test. In addition, leukocyte counts and serum total protein (TP) levels were determined. The results revealed that aging, high serum levels, and stress-coping factors (e.g., having hobbies, keeping pets, and close links with friends or family) significantly correlated with preferable neutrophil functions. In addition, significant effects of lifestyle factors on the balance between phagocytosis and subsequent superoxide production were observed. Thus, the results of the present study suggest that there are correlations between neutrophil functions and lifestyle factors in the elderly.
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U2 - 10.1002/jcla.10152
DO - 10.1002/jcla.10152
M3 - Article
C2 - 12357457
AN - SCOPUS:0036391670
SN - 0887-8013
VL - 16
SP - 266
EP - 272
JO - Journal of Clinical Laboratory Analysis
JF - Journal of Clinical Laboratory Analysis
IS - 5
ER -