Rheological property of artificial red cells suspended in plasma expanders (water soluble polymers)

Atsushi Satoh; Hiromi Sakai; Shinji Takeoka; Eishun Tsuchida

Rheological property of artificial red cells suspended in plasma expanders (water soluble polymers)

Atsushi Satoh^*, Hiromi Sakai, Shinji Takeoka, Eishun Tsuchida

^*この研究の対応する著者

先進理工学部

研究成果: Paper › 査読

抄録

Hemoglobin-vesicles (HbVs) are developed as artificial red cells. The HbV suspension does not have a detectable colloid osmotic pressure. Therefore, the intravenous infusion of large amount of HbV requires an addition of a plasma expander (e.g., albumin, polysaccharides, or gelatin solution). Here, we analyzed the viscoelastic property of these suspensions. In the case of HbVs suspended in albumin, the viscoelastic property showed approximately Newtonian. Other suspensions showed shear thinning due to reversible aggregation of HbVs induced by the interaction with the plasma expanders.

本文言語	English
ページ数	1
出版ステータス	Published - 2006 10月 19
イベント	55th SPSJ Annual Meeting - Nagoya, Japan 継続期間: 2006 5月 24 → 2006 5月 26

Conference

Conference	55th SPSJ Annual Meeting
国/地域	Japan
City	Nagoya
Period	06/5/24 → 06/5/26

ASJC Scopus subject areas

工学（全般）

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author = "Atsushi Satoh and Hiromi Sakai and Shinji Takeoka and Eishun Tsuchida",

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AU - Satoh, Atsushi

AU - Sakai, Hiromi

AU - Takeoka, Shinji

AU - Tsuchida, Eishun

PY - 2006/10/19

Y1 - 2006/10/19

N2 - Hemoglobin-vesicles (HbVs) are developed as artificial red cells. The HbV suspension does not have a detectable colloid osmotic pressure. Therefore, the intravenous infusion of large amount of HbV requires an addition of a plasma expander (e.g., albumin, polysaccharides, or gelatin solution). Here, we analyzed the viscoelastic property of these suspensions. In the case of HbVs suspended in albumin, the viscoelastic property showed approximately Newtonian. Other suspensions showed shear thinning due to reversible aggregation of HbVs induced by the interaction with the plasma expanders.

AB - Hemoglobin-vesicles (HbVs) are developed as artificial red cells. The HbV suspension does not have a detectable colloid osmotic pressure. Therefore, the intravenous infusion of large amount of HbV requires an addition of a plasma expander (e.g., albumin, polysaccharides, or gelatin solution). Here, we analyzed the viscoelastic property of these suspensions. In the case of HbVs suspended in albumin, the viscoelastic property showed approximately Newtonian. Other suspensions showed shear thinning due to reversible aggregation of HbVs induced by the interaction with the plasma expanders.

KW - Artificial red cell

KW - Hemorheology

KW - Liposome

KW - Plasma expander

KW - Polyethylene glycol

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M3 - Paper

AN - SCOPUS:33749824930

T2 - 55th SPSJ Annual Meeting

Y2 - 24 May 2006 through 26 May 2006

ER -

Rheological property of artificial red cells suspended in plasma expanders (water soluble polymers)

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Conference

ASJC Scopus subject areas

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