Sodium 1-(12-hydroxy)octadecanyl sulfate, an MMP2 inhibitor, isolated from a tunicate of the family polyclinidae

Masaki Fujita; Yoichi Nakao; Shigeki Matsunaga; Teruaki Nishikawa; Nobuhiro Fusetani

doi:10.1021/np020250o

Sodium 1-(12-hydroxy)octadecanyl sulfate, an MMP2 inhibitor, isolated from a tunicate of the family polyclinidae

Masaki Fujita, Yoichi Nakao, Shigeki Matsunaga, Teruaki Nishikawa, Nobuhiro Fusetani^*

^*この研究の対応する著者

研究成果: Article › 査読

27 被引用数 (Scopus)

抄録

Sodium 1-(12-hydroxy)octadecanyl sulfate (1) was isolated from a marine tunicate as a matrix metalloproteinase 2 (MMP2) inhibitor.¹ The structure was elucidated by a combination of spectroscopic and chemical methods. Compound 1 inhibited MMP2 with an IC₅₀ value of 9.0 μg/mL.

本文言語	English
ページ（範囲）	1936-1938
ページ数	3
ジャーナル	Journal of Natural Products
巻	65
号	12
DOI	https://doi.org/10.1021/np020250o
出版ステータス	Published - 2002 12月 1
外部発表	はい

ASJC Scopus subject areas

分析化学
分子医療
薬理学
薬科学
創薬
補完代替医療
有機化学

UN SDG

この成果は、次の持続可能な開発目標に貢献しています

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title = "Sodium 1-(12-hydroxy)octadecanyl sulfate, an MMP2 inhibitor, isolated from a tunicate of the family polyclinidae",

abstract = "Sodium 1-(12-hydroxy)octadecanyl sulfate (1) was isolated from a marine tunicate as a matrix metalloproteinase 2 (MMP2) inhibitor.1 The structure was elucidated by a combination of spectroscopic and chemical methods. Compound 1 inhibited MMP2 with an IC50 value of 9.0 μg/mL.",

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AU - Nishikawa, Teruaki

AU - Fusetani, Nobuhiro

PY - 2002/12/1

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N2 - Sodium 1-(12-hydroxy)octadecanyl sulfate (1) was isolated from a marine tunicate as a matrix metalloproteinase 2 (MMP2) inhibitor.1 The structure was elucidated by a combination of spectroscopic and chemical methods. Compound 1 inhibited MMP2 with an IC50 value of 9.0 μg/mL.

AB - Sodium 1-(12-hydroxy)octadecanyl sulfate (1) was isolated from a marine tunicate as a matrix metalloproteinase 2 (MMP2) inhibitor.1 The structure was elucidated by a combination of spectroscopic and chemical methods. Compound 1 inhibited MMP2 with an IC50 value of 9.0 μg/mL.

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Sodium 1-(12-hydroxy)octadecanyl sulfate, an MMP2 inhibitor, isolated from a tunicate of the family polyclinidae

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ASJC Scopus subject areas

UN SDG

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