TY - JOUR
T1 - Studies into asymmetric catalysis of the Nozaki-Hiyama allenylation
AU - Inoue, Masahiro
AU - Nakada, Masahisa
PY - 2005/12/23
Y1 - 2005/12/23
N2 - (Chemical Equation Presented) From aldehydes to allenic alcohols: Studies into the asymmetric catalysis of the Nozaki-Hiyama allenylation are described. Ligand 1a is effective for the enantioselective allenylations of various aldehydes, with the generation of products with ee values ranging from 72-83%. The products can be easily desilylated or used as allenylsilanes. DIPEA = diisopropylethylamine, DMI = 1,3-dimethyl-2-imidazolidinone, DMS = dimethylsilyl, TMS = trimethylsilyl.
AB - (Chemical Equation Presented) From aldehydes to allenic alcohols: Studies into the asymmetric catalysis of the Nozaki-Hiyama allenylation are described. Ligand 1a is effective for the enantioselective allenylations of various aldehydes, with the generation of products with ee values ranging from 72-83%. The products can be easily desilylated or used as allenylsilanes. DIPEA = diisopropylethylamine, DMI = 1,3-dimethyl-2-imidazolidinone, DMS = dimethylsilyl, TMS = trimethylsilyl.
KW - Allenes
KW - Allenic alcohols
KW - Asymmetric catalysis
KW - Chromium
KW - Enantioselectivity
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U2 - 10.1002/anie.200502871
DO - 10.1002/anie.200502871
M3 - Article
C2 - 16317780
AN - SCOPUS:29544452399
SN - 1433-7851
VL - 45
SP - 252
EP - 255
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 2
ER -