Surface modification of hemoglobin vesicles with poly(ethylene glycol) and effects on aggregation, viscosity, and blood flow during 90% exchange transfusion in anesthetized rats

Engineering & Materials Science

• Hemoglobin 89%
• Polyethylene glycols 82%
• Rats 75%
• Surface treatment 66%
• Blood 58%
• Agglomeration 55%
• Viscosity 51%
• Hemodynamics 8%
• Shear deformation 7%
• Phospholipids 5%
• Molecular interactions 5%
• Pore size 4%
• Optical microscopy 3%
• Surface properties 3%
• Cells 3%
• Membranes 2%
• Gases 2%

Medicine & Life Sciences

• PEG-hemoglobin 100%
• Blood Viscosity 81%
• Ethylene Glycol 78%
• Albumins 54%
• Hemoglobins 51%
• Viscosity 21%
• Capillaries 9%
• Theology 8%
• Blood Substitutes 6%
• Surface Properties 6%
• phosphatidylethanolamine 5%
• Blood Circulation 5%
• Abdominal Aorta 5%
• Vascular Resistance 4%
• Phospholipids 4%
• Suspensions 4%
• Gases 4%
• Microscopy 4%
• Wistar Rats 4%
• Hemodynamics 3%
• Membranes 2%

Chemical Compounds

• Hemoglobin 59%
• Surface Modification 54%
• Poly(ethylene Glycol) 50%
• Flow 40%
• Shear 6%
• Hemodynamic 5%
• Membrane Filter 4%
• Phosphatidylethanolamine 4%
• Steric Hindrance 3%
• Tension 3%
• Optical Microscopy 3%
• Phospholipid 2%
• Pore Size 2%
• Suspension 2%
• Red 2%
• Surface 2%
• Resistance 2%
• Modification 1%
• Gas 1%
• pH Value 1%
• Time 1%