Synchronized stereocontrol of planar chirality by crystallization-induced asymmetric transformation

Nobuhiro Kanomata; Gou Mishima; Jun Onozato

doi:10.1016/j.tetlet.2008.11.021

Synchronized stereocontrol of planar chirality by crystallization-induced asymmetric transformation

Nobuhiro Kanomata^*, Gou Mishima, Jun Onozato

^*この研究の対応する著者

先進理工学部

研究成果: Article › 査読

19 被引用数 (Scopus)

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Synchronized stereocontrol of two planar-chiral units was accomplished by using crystallization-induced asymmetric transformation (CIAT) of cyclophane-type bridged bisnicotinate derivatives 5b and 7. After screening various linkers, (S)-2-amino-1-butanol and (S)-tert-leucinol were found to be the most effective for CIAT of the corresponding bridged bisnicotinate 5b and 7, respectively, whose diastereomeric ratio finally reached 97% and 88%, respectively.

本文言語	English
ページ（範囲）	409-412
ページ数	4
ジャーナル	Tetrahedron Letters
巻	50
号	4
DOI	https://doi.org/10.1016/j.tetlet.2008.11.021
出版ステータス	Published - 2009 1月 28

ASJC Scopus subject areas

生化学
創薬
有機化学

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10.1016/j.tetlet.2008.11.021

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title = "Synchronized stereocontrol of planar chirality by crystallization-induced asymmetric transformation",

abstract = "Synchronized stereocontrol of two planar-chiral units was accomplished by using crystallization-induced asymmetric transformation (CIAT) of cyclophane-type bridged bisnicotinate derivatives 5b and 7. After screening various linkers, (S)-2-amino-1-butanol and (S)-tert-leucinol were found to be the most effective for CIAT of the corresponding bridged bisnicotinate 5b and 7, respectively, whose diastereomeric ratio finally reached 97% and 88%, respectively.",

author = "Nobuhiro Kanomata and Gou Mishima and Jun Onozato",

note = "Funding Information: The authors acknowledge The Asahi Glass Foundation for financial support to this work. ",

year = "2009",

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doi = "10.1016/j.tetlet.2008.11.021",

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T1 - Synchronized stereocontrol of planar chirality by crystallization-induced asymmetric transformation

AU - Kanomata, Nobuhiro

AU - Mishima, Gou

AU - Onozato, Jun

N1 - Funding Information: The authors acknowledge The Asahi Glass Foundation for financial support to this work.

PY - 2009/1/28

Y1 - 2009/1/28

N2 - Synchronized stereocontrol of two planar-chiral units was accomplished by using crystallization-induced asymmetric transformation (CIAT) of cyclophane-type bridged bisnicotinate derivatives 5b and 7. After screening various linkers, (S)-2-amino-1-butanol and (S)-tert-leucinol were found to be the most effective for CIAT of the corresponding bridged bisnicotinate 5b and 7, respectively, whose diastereomeric ratio finally reached 97% and 88%, respectively.

AB - Synchronized stereocontrol of two planar-chiral units was accomplished by using crystallization-induced asymmetric transformation (CIAT) of cyclophane-type bridged bisnicotinate derivatives 5b and 7. After screening various linkers, (S)-2-amino-1-butanol and (S)-tert-leucinol were found to be the most effective for CIAT of the corresponding bridged bisnicotinate 5b and 7, respectively, whose diastereomeric ratio finally reached 97% and 88%, respectively.

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U2 - 10.1016/j.tetlet.2008.11.021

DO - 10.1016/j.tetlet.2008.11.021

M3 - Article

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SN - 0040-4039

VL - 50

SP - 409

EP - 412

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 4

ER -

Synchronized stereocontrol of planar chirality by crystallization-induced asymmetric transformation

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