@article{70d9cf03d69a4cf99f7a8fd1f7ade5d4,
title = "Synergistic effects of stellated fibrous mesoporous silica and synthetic dsRNA analogues for cancer immunotherapy",
abstract = "Stellated fibrous mesoporous silica nanospheres significantly improve the cellular uptake of cancer antigen and the maturation of bone marrow derived dendritic cells in vitro. Moreover, the combination of poly(I:C) with stellated fibrous MS nanospheres markedly decreases the necessary dose of poly(I:C) for anti-tumor immunity, and thus opens new opportunities for the future clinical application of poly(I:C) in cancer immunotherapy.",
author = "Xiupeng Wang and Xia Li and Atsuo Ito and Yu Sogo and Yohei Watanabe and Kaoru Hashimoto and Atsushi Yamazaki and Tadao Ohno and Tsuji, {Noriko M.}",
note = "Funding Information: We thank Ms Hisako Sugino and Ms Kazuko Yoshiyuki for technical assistance. We thank Prof. Koji Tsuboi at the University of Tsukuba for fruitful discussion. This study was supported in part by JSPS KAKENHI Grant Number 17K01399 and 26750162. This study was also supported in part by the NIMS Molecule & Material Synthesis Platform and NIMS Microstructural Characterization Platform as a program of {\textquoteleft}{\textquoteleft}Nanotechnology Platform{\textquoteright}{\textquoteright} of the Ministry of Education, Culture, Sports, Science and Technology (MEXT), Japan. Publisher Copyright: {\textcopyright} 2018 The Royal Society of Chemistry.",
year = "2018",
doi = "10.1039/c7cc08222c",
language = "English",
volume = "54",
pages = "1057--1060",
journal = "Chemical Communications",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
number = "9",
}
