抄録
Fluorination of allyl β-keto carboxylates using N-fluoro-2,4,6-pyridinium triflate gave allyl α-fluoro-β-keto carboxylates. Reaction of allyl α-fluoro-β-keto carboxylates with formic acid in the presence of palladium-phosphine catalyst gave α-fluoro ketones. When the palladium-catalyzed reaction was carried out without formic acid, the decarboxylation-allylation took place to give α-fluoro-allylketones. Decarboxylation-dehydrogenation to afford α-fluoro-α,β-unsaturated ketones was carried out with palladium catalysts in acetonitrile.
| 本文言語 | English |
|---|---|
| ページ（範囲） | 487-495 |
| ページ数 | 9 |
| ジャーナル | Tetrahedron |
| 巻 | 50 |
| 号 | 2 |
| DOI | |
| 出版ステータス | Published - 1991 |
ASJC Scopus subject areas
- 生化学
- 有機化学
- 創薬