Synthetic studies on the taxane skeleton: Construction of eight-membered carbocyclic rings by the intramolecular B-alkyl Suzuki-Miyaura cross-coupling reaction

Hatsuo Kawada; Mitsuhiro Iwamoto; Masayuki Utsugi; Masayuki Miyano; Masahisa Nakada

doi:10.1021/ol0481939

Synthetic studies on the taxane skeleton: Construction of eight-membered carbocyclic rings by the intramolecular B-alkyl Suzuki-Miyaura cross-coupling reaction

Hatsuo Kawada, Mitsuhiro Iwamoto, Masayuki Utsugi, Masayuki Miyano, Masahisa Nakada^*

^*この研究の対応する著者

先進理工学部

研究成果: Article › 査読

24 被引用数 (Scopus)

抄録

(Chemical equation presented) Construction of eight-membered carbocyclic rings via the intramolecular B-alkyl Suzuki-Miyaura cross-coupling reaction has been studied. This protocol proved its potency through the formation of the eight-membered ring possessing a quaternary carbon on its ring in high yield, affording promise of a new access to the eight-membered ring of Taxol.

本文言語	English
ページ（範囲）	4491-4494
ページ数	4
ジャーナル	Organic Letters
巻	6
号	24
DOI	https://doi.org/10.1021/ol0481939
出版ステータス	Published - 2004 11月 25

ASJC Scopus subject areas

生化学
物理化学および理論化学
有機化学

文献へのアクセス

10.1021/ol0481939

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引用スタイル

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