The effect of active pedaling combined with electrical stimulation on spinal reciprocal inhibition

Tomofumi Yamaguchi, Toshiyuki Fujiwara*, Kei Saito, Shigeo Tanabe, Yoshihiro Muraoka, Yohei Otaka, Rieko Osu, Tetsuya Tsuji, Kimitaka Hase, Meigen Liu


研究成果: Article査読

24 被引用数 (Scopus)


Objective: Pedaling is widely used for rehabilitation of locomotion because it induces muscle activity very similar to locomotion. Afferent stimulation is important for the modulation of spinal reflexes. Furthermore, supraspinal modulation plays an important role in spinal plasticity induced by electrical stimulation. We, therefore, expected that active pedaling combined with electrical stimulation could induce strong after-effects on spinal reflexes. Design: Twelve healthy adults participated in this study. They were instructed to perform 7. min of pedaling. We applied electrical stimulation to the common peroneal nerve during the extension phase of the pedaling cycle. We assessed reciprocal inhibition using a soleus H-reflex conditioning-test paradigm. The magnitude of reciprocal inhibition was measured before, immediately after, 15 and 30. min after active pedaling alone, electrical stimulation alone and active pedaling combined with electrical stimulation (pedaling. +. ES). Results: The amount of reciprocal inhibition was significantly increased after pedaling. +. ES. The after-effect of pedaling. +. ES on reciprocal inhibition was more prominent and longer lasting compared with pedaling or electrical stimulation alone. Conclusions: Pedaling. +. ES could induce stronger after-effects on spinal reciprocal inhibitory neurons compared with either intervention alone. Pedaling. +. ES might be used as a tool to improve locomotion and functional abnormalities in the patient with central nervous lesion.

ジャーナルJournal of Electromyography and Kinesiology
出版ステータスPublished - 2013 2月

ASJC Scopus subject areas

  • 神経科学(その他)
  • 生物理学
  • 臨床神経学


「The effect of active pedaling combined with electrical stimulation on spinal reciprocal inhibition」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。