@article{3fd0745273fb4c6cbe191c086a3eb32f,
title = "The first total synthesis and structural determination of YCM1008A",
abstract = "The first total synthesis and structural determination of YCM1008A, a Ca2+ signaling inhibitor, have been achieved. The N-methoxy pyrano-pyridone moiety was synthesized by successive O- and N-conjugate additions with diketoamide 15. The absolute structure was determined to be (2R,3R,4S,8′R)-configuration.",
author = "Kuniaki Tatsuta and Takahiro Yamaguchi and Yusuke Tsuda and Yumiko Yamaguchi and Nobutaka Hattori and Hiroshi Nagai and Seijiro Hosokawa",
note = "Funding Information: Special thanks to Drs. Y. Kanda and M. Ichimura, Kyowa Hakko Kogyo Co. Ltd, for an authentic sample and spectral data of YCM1008A. This work was financially supported by the 21COE {\textquoteleft}Center for Practical Nano-Chemistry{\textquoteright}, the Consolidated Research Institute for Advanced Science and Medical Care, and Scientific Research on Priority Area {\textquoteleft}Creation of Biologically Functional Molecules{\textquoteright} from the Ministry of Education, Culture, Sports, Science, and Technology. ",
year = "2007",
month = jun,
day = "11",
doi = "10.1016/j.tetlet.2007.04.074",
language = "English",
volume = "48",
pages = "4187--4190",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "24",
}