TY - JOUR
T1 - The multiple sample injector using improved sheath flow to prevent sample dilution
AU - Kanai, Masaki
AU - Ikeda, Shingo
AU - Tanaka, Junichi
AU - Go, Jeung Sang
AU - Nakanishi, Hiroaki
AU - Shoji, Shuichi
N1 - Funding Information:
This work was supported by Bio-oriented Technology Research Advancement Institution for Research and Development Program for New Bio-industry Initiatives, Japanese Ministry of Education, Culture Sports, Science & Technology Grant-in-Aid for COE Research, Scientific Research (B) No. 12450167, Scientific Research Priority Area (B) No. 13124209, Japan Society for the Promotion Science Grant-in-Aid for Creative Scientific Research No. 13GS0024 and 21COE “Practical Nano-Chemistry” from MEXT, Japan.
PY - 2004/3/1
Y1 - 2004/3/1
N2 - This paper presents a sheath flow multiple sample injector that realizes concentration-conservative sample injection. Stepwise flow is used to reduce the dilution of the sample reagent. Based on the CFD simulation results, it is estimated that sample reagent is diluted to 94% in a conventional sample injector. With stepwise flow, however, the level of dilution is reduced and the average concentration is estimated to be near 100%. For the experiment evaluation, a sample injector is fabricated and the sample injection using stepwise flow is visualized using a fluorescent measuring system. The accuracy of the injected sample volume and the feasibility of multiple sample injection are evaluated based on the experiment results.
AB - This paper presents a sheath flow multiple sample injector that realizes concentration-conservative sample injection. Stepwise flow is used to reduce the dilution of the sample reagent. Based on the CFD simulation results, it is estimated that sample reagent is diluted to 94% in a conventional sample injector. With stepwise flow, however, the level of dilution is reduced and the average concentration is estimated to be near 100%. For the experiment evaluation, a sample injector is fabricated and the sample injection using stepwise flow is visualized using a fluorescent measuring system. The accuracy of the injected sample volume and the feasibility of multiple sample injection are evaluated based on the experiment results.
KW - CFD simulation
KW - Sample injector
KW - Sheath flow
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U2 - 10.1016/j.sna.2003.08.014
DO - 10.1016/j.sna.2003.08.014
M3 - Conference article
AN - SCOPUS:0442311893
SN - 0924-4247
VL - 111
SP - 32
EP - 36
JO - Sensors and Actuators, A: Physical
JF - Sensors and Actuators, A: Physical
IS - 1
T2 - Micromechanics Section of Sensors and Actuators, based on
Y2 - 19 January 2003 through 23 January 2003
ER -