The purpose of this study was to verifying effectiveness of the guidelines for supporting resilience enhancement. Moreover, we aimed to discuss the effective way to use the guidelines based statistical data. The two fitness centers of the Metropolitan area joined this research in Japan. The fitness clubs approached to enhance resilience using the guidelines for a month or three months. The samples were 18 employees (Center A: 10, Center B: 8) completing the before-and-after evaluation using a questionnaire about resilience. The effect size (r) of result for paired t-test was pointed as the evaluate index for effectiveness of the activities to enhance resilience with the guidelines. As the result, center A’s resilience increased (r = 0.15 − 0.64), center B’s resilience decreased (r = 0.23 − 0.80). The organizational improvement activities including the improvement organizational process and interaction cause more effective resilience enhancement rather than the activities aiming to individual ability development to strengthen individual weakness.