@article{fbcb5a10a48448d9b76d2a6ad0331e10,
title = "Total synthesis of (-)-FR182877 through tandem IMDA-IMHDA reactions and stereoselective transition-metal-mediated transformations",
abstract = "Intelligent design: The total synthesis of the cytotoxic (-)- FR182877 relies on 1) tandem Diels-Alder reactions to close rings A-D (see scheme), 2) a palladium-mediated 7- exo-trig reaction, and 3) an iridium-mediated isomerization followed by epimerization and stereoselective reduction.",
keywords = "Antitumor Agents, Cycloaddition, Natural products, Polycycles, Strained molecules",
author = "Natsumi Tanaka and Takahiro Suzuki and Takehiko Matsumura and Yosuke Hosoya and Masahisa Nakada",
year = "2009",
month = mar,
day = "23",
doi = "10.1002/anie.200900097",
language = "English",
volume = "48",
pages = "2580--2583",
journal = "Angewandte Chemie - International Edition",
issn = "1433-7851",
publisher = "John Wiley and Sons Ltd",
number = "14",
}