抄録
A general method for immobilization of capture ligands in a single channel of extended nanospace depth is reported. For multiplexed analysis in a single channel, several ligands must be immobilized in the same channel. Since the bonding procedure (by heat/ HF) for glass and fused silica chips would destroy the ligands, we designed and synthesized a UV-activated linker for covalent ligand attachment inside the channels after fabrication. A modified mask aligner was used to align OHP or Cr masks to the channels to facilitate immobilization of the DNA capture oligos to pre-defined areas.
| 本文言語 | English |
|---|---|
| ホスト出版物のタイトル | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of MicroTAS 2008 Conference |
| 出版社 | Chemical and Biological Microsystems Society |
| ページ | 1528-1530 |
| ページ数 | 3 |
| 出版ステータス | Published - 2008 |
| 外部発表 | はい |
| イベント | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 - San Diego, CA 継続期間: 2008 10月 12 → 2008 10月 16 |
Other
| Other | 12th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2008 |
|---|---|
| City | San Diego, CA |
| Period | 08/10/12 → 08/10/16 |
ASJC Scopus subject areas
- 化学工学（その他）
- バイオエンジニアリング