TY - JOUR
T1 - Walking nanothermometers
T2 - Spatiotemporal temperature measurement of transported acidic organelles in single living cells
AU - Oyama, Kotaro
AU - Takabayashi, Masao
AU - Takei, Yoshiaki
AU - Arai, Satoshi
AU - Takeoka, Shinji
AU - Ishiwata, Shin'Ichi
AU - Suzuki, Madoka
N1 - Copyright:
Copyright 2019 Elsevier B.V., All rights reserved.
PY - 2012/5/7
Y1 - 2012/5/7
N2 - We fabricated fluorescent nanoparticles which monitor temperature changes without sensitivity to pH (4-10) and ionic strength (0-500 mM). The nanothermometers spontaneously enter living HeLa cells via endocytosis, enclosed in acidic organelles, i.e., endosome/lysosome, and then transported along microtubules in a temperature-dependent manner, working as "walking nanothermometers".
AB - We fabricated fluorescent nanoparticles which monitor temperature changes without sensitivity to pH (4-10) and ionic strength (0-500 mM). The nanothermometers spontaneously enter living HeLa cells via endocytosis, enclosed in acidic organelles, i.e., endosome/lysosome, and then transported along microtubules in a temperature-dependent manner, working as "walking nanothermometers".
UR - http://www.scopus.com/inward/record.url?scp=84859798807&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84859798807&partnerID=8YFLogxK
U2 - 10.1039/c2lc00014h
DO - 10.1039/c2lc00014h
M3 - Article
C2 - 22437040
AN - SCOPUS:84859798807
SN - 1473-0197
VL - 12
SP - 1591
EP - 1593
JO - Lab on a Chip - Miniaturisation for Chemistry and Biology
JF - Lab on a Chip - Miniaturisation for Chemistry and Biology
IS - 9
ER -